Elaborate uORF/IRES features control expression and localization of human glycyl-tRNA synthetase

The canonical activity of glycyl-tRNA synthetase (GARS) is to charge glycine onto its cognate tRNAs. However, outside translation, GARS also participates in many other functions. A single gene encodes both the cytosolic and mitochondrial forms of GARS but 2 mRNA isoforms were identified. Using immun...

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Bibliografiske detaljer
Udgivet i:RNA Biol
Main Authors: Alexandrova, Jana, Paulus, Caroline, Rudinger-Thirion, Joëlle, Jossinet, Fabrice, Frugier, Magali
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829322/
https://ncbi.nlm.nih.gov/pubmed/26327585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1086866
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