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Misfolded human tRNA isodecoder binds and neutralizes a 3′ UTR-embedded Alu element

Several classes of small noncoding RNAs are key players in cellular metabolism including mRNA decoding, RNA processing, and mRNA stability. Here we show that a tRNA(Asp) isodecoder, corresponding to a human tRNA-derived sequence, binds to an embedded Alu RNA element contained in the 3′ UTR of the hu...

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Hlavní autoři: Rudinger-Thirion, Joëlle, Lescure, Alain, Paulus, Caroline, Frugier, Magali
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189049/
https://ncbi.nlm.nih.gov/pubmed/21896722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103698108
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