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D-repeat in the XIST gene is required for X chromosome inactivation

XIST is a long non-coding RNA, which expressed exclusively from the inactive X chromosome. Although it has been revealed that the A-repeat contributes to the X chromosome inactivation (X-inactivation), the role of the longest D-repeat has not yet been investigated. Here, a sgRNA directed CRISPR/Cas9...

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Dettagli Bibliografici
Pubblicato in:RNA Biol
Autori principali: Lv, Qingyan, Yuan, Lin, Song, Yuning, Sui, Tingting, Li, Zhanjun, Lai, Liangxue
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829313/
https://ncbi.nlm.nih.gov/pubmed/26786668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1137420
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