Non-sequential and multi-step splicing of the dystrophin transcript

The dystrophin protein encoding DMD gene is the longest human gene. The 2.2 Mb long human dystrophin transcript takes 16 hours to be transcribed and is co-transcriptionally spliced. It contains long introns (24 over 10kb long, 5 over 100kb long) and the heterogeneity in intron size makes it an ideal...

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Detalles Bibliográficos
Publicado en:RNA Biol
Main Authors: Gazzoli, Isabella, Pulyakhina, Irina, Verwey, Nisha E., Ariyurek, Yavuz, Laros, Jeroen F. J., 't Hoen, Peter A. C., Aartsma-Rus, Annemieke
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829307/
https://ncbi.nlm.nih.gov/pubmed/26670121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1125074
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