Non-sequential and multi-step splicing of the dystrophin transcript

The dystrophin protein encoding DMD gene is the longest human gene. The 2.2 Mb long human dystrophin transcript takes 16 hours to be transcribed and is co-transcriptionally spliced. It contains long introns (24 over 10kb long, 5 over 100kb long) and the heterogeneity in intron size makes it an ideal...

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Bibliografiska uppgifter
I publikationen:RNA Biol
Huvudupphovsmän: Gazzoli, Isabella, Pulyakhina, Irina, Verwey, Nisha E., Ariyurek, Yavuz, Laros, Jeroen F. J., 't Hoen, Peter A. C., Aartsma-Rus, Annemieke
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829307/
https://ncbi.nlm.nih.gov/pubmed/26670121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1125074
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