Complex Minigene Library Vaccination for Discovery of Pre-Erythrocytic Plasmodium T Cell Antigens

Development of a subunit vaccine targeting liver-stage Plasmodium parasites requires the identification of antigens capable of inducing protective T cell responses. However, traditional methods of antigen identification are incapable of evaluating T cell responses against large numbers of proteins e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Stone, Brad C., Kas, Arnold, Billman, Zachary P., Fuller, Deborah H., Fuller, James T., Shendure, Jay, Murphy, Sean C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829254/
https://ncbi.nlm.nih.gov/pubmed/27070430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153449
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