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A T-cell response to a liver-stage Plasmodium antigen is not boosted by repeated sporozoite immunizations

Development of an antimalarial subunit vaccine inducing protective cytotoxic T lymphocyte (CTL)-mediated immunity could pave the way for malaria eradication. Experimental immunization with sporozoites induces this type of protective response, but the extremely large number of proteins expressed by P...

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Detalhes bibliográficos
Main Authors: Murphy, Sean C., Kas, Arnold, Stone, Brad C., Bevan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625320/
https://ncbi.nlm.nih.gov/pubmed/23530242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303834110
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