MiR-206 Attenuates Denervation-Induced Skeletal Muscle Atrophy in Rats Through Regulation of Satellite Cell Differentiation via TGF-β1, Smad3, and HDAC4 Signaling

BACKGROUND: Denervation-induced skeletal muscle atrophy results in significant biochemical and physiological changes potentially leading to devastating outcomes including increased mortality. Effective treatments for skeletal muscle diseases are currently not available. Muscle-specific miRNAs, such...

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Foilsithe in:Med Sci Monit
Main Authors: Huang, Qiang-Kai, Qiao, Hu-Yun, Fu, Ming-Huan, Li, Gang, Li, Wen-Bin, Chen, Zhi, Wei, Jian, Liang, Bing-Sheng
Formáid: Artigo
Teanga:Inglês
Foilsithe: International Scientific Literature, Inc. 2016
Ábhair:
Animal Study
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829125/
https://ncbi.nlm.nih.gov/pubmed/27054781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.897909
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