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Absence of Peroxiredoxin 6 Amplifies the Effect of Oxidant Stress on Mobility and SCSA/CMA3 Defined Chromatin Quality and Impairs Fertilizing Ability of Mouse Spermatozoa

Oxidative stress, the imbalance between reactive oxygen species production and antioxidant defenses, is associated with male infertility. Peroxiredoxins (PRDXs) are antioxidant enzymes with a wide distribution in spermatozoa. PRDX6 is highly abundant and located in all subcellular compartments of th...

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Detaylı Bibliyografya
Yayımlandı:Biol Reprod
Asıl Yazarlar: Ozkosem, Burak, Feinstein, Sheldon I., Fisher, Aron B., O'Flaherty, Cristian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for the Study of Reproduction, Inc. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829091/
https://ncbi.nlm.nih.gov/pubmed/26792942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.137646
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