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Absence of Peroxiredoxin 6 Amplifies the Effect of Oxidant Stress on Mobility and SCSA/CMA3 Defined Chromatin Quality and Impairs Fertilizing Ability of Mouse Spermatozoa

Oxidative stress, the imbalance between reactive oxygen species production and antioxidant defenses, is associated with male infertility. Peroxiredoxins (PRDXs) are antioxidant enzymes with a wide distribution in spermatozoa. PRDX6 is highly abundant and located in all subcellular compartments of th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Reprod
Main Authors: Ozkosem, Burak, Feinstein, Sheldon I., Fisher, Aron B., O'Flaherty, Cristian
Format: Artigo
Jezik:Inglês
Izdano: Society for the Study of Reproduction, Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829091/
https://ncbi.nlm.nih.gov/pubmed/26792942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.137646
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