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Absence of Peroxiredoxin 6 Amplifies the Effect of Oxidant Stress on Mobility and SCSA/CMA3 Defined Chromatin Quality and Impairs Fertilizing Ability of Mouse Spermatozoa

Oxidative stress, the imbalance between reactive oxygen species production and antioxidant defenses, is associated with male infertility. Peroxiredoxins (PRDXs) are antioxidant enzymes with a wide distribution in spermatozoa. PRDX6 is highly abundant and located in all subcellular compartments of th...

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Detalles Bibliográficos
Publicado en:Biol Reprod
Autores principales: Ozkosem, Burak, Feinstein, Sheldon I., Fisher, Aron B., O'Flaherty, Cristian
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829091/
https://ncbi.nlm.nih.gov/pubmed/26792942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.137646
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