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Targeting the WASF3-CYFIP1 complex using stapled peptides suppresses cancer cell invasion

Activation of the WASF3 protein by extracellular stimuli promotes actin cytoskeleton reorganization and facilitates cancer cell invasion, whereas WASF3 depletion suppresses invasion and metastasis. In quiescent cells, the interaction between WASF3 and a complex of proteins including CYFIP1 acts as a...

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Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: Teng, Yong, Bahassan, Abdulaziz, Dong, Dayong, Hanold, Laura E, Ren, Xiaoou, Kennedy, Eileen J, Cowell, John K
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828974/
https://ncbi.nlm.nih.gov/pubmed/26676744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1680
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