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Uracil DNA glycosylase interacts with the p32 subunit of the replication protein A complex to modulate HIV-1 reverse transcription for optimal virus dissemination

BACKGROUND: Through incorporation into virus particles, the HIV-1 Vpr protein participates in the early steps of the virus life cycle by influencing the reverse transcription process. We previously showed that this positive impact on reverse transcription was related to Vpr binding to the uracil DNA...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Herate, Cecile, Vigne, Clarisse, Guenzel, Carolin A., Lambele, Marie, Rouyez, Marie-Christine, Benichou, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828845/
https://ncbi.nlm.nih.gov/pubmed/27068393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0257-x
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