Uracil DNA glycosylase interacts with the p32 subunit of the replication protein A complex to modulate HIV-1 reverse transcription for optimal virus dissemination

BACKGROUND: Through incorporation into virus particles, the HIV-1 Vpr protein participates in the early steps of the virus life cycle by influencing the reverse transcription process. We previously showed that this positive impact on reverse transcription was related to Vpr binding to the uracil DNA...

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Enregistré dans:
Détails bibliographiques
Publié dans:Retrovirology
Auteurs principaux: Herate, Cecile, Vigne, Clarisse, Guenzel, Carolin A., Lambele, Marie, Rouyez, Marie-Christine, Benichou, Serge
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828845/
https://ncbi.nlm.nih.gov/pubmed/27068393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0257-x
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