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Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity

Diet and microbiome derived indole derivatives are known to activate the ligand induced transcription factor, the Aryl hydrocarbon Receptor (AhR). While the current understanding of AhR biology has confirmed its role in mucosal lymphocytes, its function in intestinal antigen presenting cells (APCs)...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chng, Song Hui, Kundu, Parag, Dominguez-Brauer, Carmen, Teo, Wei Ling, Kawajiri, Kaname, Fujii-Kuriyama, Yoshiaki, Mak, Tak Wah, Pettersson, Sven
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828637/
https://ncbi.nlm.nih.gov/pubmed/27068235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23820
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