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Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity

Diet and microbiome derived indole derivatives are known to activate the ligand induced transcription factor, the Aryl hydrocarbon Receptor (AhR). While the current understanding of AhR biology has confirmed its role in mucosal lymphocytes, its function in intestinal antigen presenting cells (APCs)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chng, Song Hui, Kundu, Parag, Dominguez-Brauer, Carmen, Teo, Wei Ling, Kawajiri, Kaname, Fujii-Kuriyama, Yoshiaki, Mak, Tak Wah, Pettersson, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828637/
https://ncbi.nlm.nih.gov/pubmed/27068235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23820
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