Methotrexate induces differentiation of human keratinocytes.

Terminal differentiation is a key element in the maintenance of tissue homeostasis in the epidermis. We show here that methotrexate (MTX) induces differentiation of human epidermal keratinocytes in vitro. MTX inhibits proliferation of keratinocytes and also induces several markers of differentiation...

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Hlavní autoři: Schwartz, P M, Barnett, S K, Atillasoy, E S, Milstone, L M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC48285/
https://ncbi.nlm.nih.gov/pubmed/1731329
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