Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium

In mice, loss of pantetheinase activity causes susceptibility to infection with Plasmodium chabaudi AS. Treatment of mice with the pantetheinase metabolite cysteamine reduces blood-stage replication of P. chabaudi and significantly increases survival. Similarly, a short exposure of Plasmodium to cys...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Exp Parasitol
Egile Nagusiak: Min-Oo, Gundula, Ayi, Kodjo, Bongfen, Silayuv E., Tam, Mifong, Radovanovic, Irena, Gauthier, Susan, Santiago, Helton, Rothfuchs, Antonio Gigliotti, Roffê, Ester, Sher, Alan, Mullick, Alaka, Fortin, Anny, Stevenson, Mary M., Kain, Kevin C., Gros, Philippe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828244/
https://ncbi.nlm.nih.gov/pubmed/20219464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2010.02.009
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