Triterpenoid saponin flaccidoside II from Anemone flaccida triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors via the MAPK-HO-1 pathway

Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive soft tissue neoplasms that are extremely rare and are frequently associated with neurofibromatosis type 1 patients. MPNSTs are typically fatal, and there is no effective treatment so far. In our previous study, we showed that fl...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Han, Lin-tao, Fang, Yin, Cao, Yan, Wu, Feng-hua, Liu, E, Mo, Guo-yan, Huang, Fang
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827896/
https://ncbi.nlm.nih.gov/pubmed/27103823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S95597
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