Standardized benchmarking in the quest for orthologs

Achieving high accuracy in orthology inference is essential for many comparative, evolutionary and functional genomic analyses, yet the true evolutionary history of genes is generally unknown and orthologs are used for very different applications across phyla, requiring different precision–recall tr...

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Udgivet i:Nat Methods
Main Authors: Altenhoff, Adrian M, Boeckmann, Brigitte, Capella-Gutierrez, Salvador, Dalquen, Daniel A, DeLuca, Todd, Forslund, Kristoffer, Huerta-Cepas, Jaime, Linard, Benjamin, Pereira, Cécile, Pryszcz, Leszek P, Schreiber, Fabian, da Silva, Alan Sousa, Szklarczyk, Damian, Train, Clément-Marie, Bork, Peer, Lecompte, Odile, von Mering, Christian, Xenarios, Ioannis, Sjölander, Kimmen, Jensen, Lars Juhl, Martin, Maria J, Muffato, Matthieu, Gabaldón, Toni, Lewis, Suzanna E, Thomas, Paul D, Sonnhammer, Erik, Dessimoz, Christophe
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827703/
https://ncbi.nlm.nih.gov/pubmed/27043882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3830
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