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A comparison of methods to adjust for continuous covariates in the analysis of randomised trials

BACKGROUND: Although covariate adjustment in the analysis of randomised trials can be beneficial, adjustment for continuous covariates is complicated by the fact that the association between covariate and outcome must be specified. Misspecification of this association can lead to reduced power, and...

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Bibliografische gegevens
Gepubliceerd in:BMC Med Res Methodol
Hoofdauteurs: Kahan, Brennan C., Rushton, Helen, Morris, Tim P., Daniel, Rhian M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827223/
https://ncbi.nlm.nih.gov/pubmed/27068456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-016-0141-3
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