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A comparison of methods to adjust for continuous covariates in the analysis of randomised trials

BACKGROUND: Although covariate adjustment in the analysis of randomised trials can be beneficial, adjustment for continuous covariates is complicated by the fact that the association between covariate and outcome must be specified. Misspecification of this association can lead to reduced power, and...

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Publicat a:BMC Med Res Methodol
Autors principals: Kahan, Brennan C., Rushton, Helen, Morris, Tim P., Daniel, Rhian M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827223/
https://ncbi.nlm.nih.gov/pubmed/27068456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-016-0141-3
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