Loss of Dopamine Phenotype Among Midbrain Neurons in Lesch–Nyhan Disease

OBJECTIVE: Lesch–Nyhan disease (LND) is caused by congenital deficiency of the purine recycling enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt). Affected patients have a peculiar neurobehavioral syndrome linked with reductions of dopamine in the basal ganglia. The purpose of the curre...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Ann Neurol
Main Authors: Göttle, Martin, Prudente, Cecilia N., Fu, Rong, Sutcliffe, Diane, Pang, Hong, Cooper, Deborah, Veledar, Emir, Glass, Jonathan D., Gearing, Marla, Visser, Jasper E., Jinnah, H. A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827147/
https://ncbi.nlm.nih.gov/pubmed/24891139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24191
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki