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Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia
Searching for genetic variants with unusual differentiation between subpopulations is an established approach for identifying signals of natural selection. However, existing methods generally require discrete subpopulations. We introduce a method that infers selection using principal components (PCs...
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| Publicado no: | Am J Hum Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4827102/ https://ncbi.nlm.nih.gov/pubmed/26924531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.12.022 |
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