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Architectural plasticity of AMPK revealed by electron microscopy and X-ray crystallography

Mammalian AMP-activated protein kinase (AMPK) acts as an important sensor of cellular energy homeostasis related with AMP/ADP to ATP ratio. The overall architecture of AMPK has been determined in either homotrimer or monomer form by electron microscopy (EM) and X-ray crystallography successively. Ac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ouyang, Yan, Zhu, Li, Li, Yifang, Guo, Miaomiao, Liu, Yang, Cheng, Jin, Zhao, Jing, Wu, Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827068/
https://ncbi.nlm.nih.gov/pubmed/27063142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24191
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