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The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy
Structural analysis of protein fibrillation is inherently challenging. Given the crucial role of fibrils in amyloid diseases, method advancement is urgently needed. A hybrid modelling approach is presented enabling detailed analysis of a highly ordered and hierarchically organized fibril of the GNNQ...
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Publicado no: | Acta Crystallogr D Biol Crystallogr |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
International Union of Crystallography
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4388266/ https://ncbi.nlm.nih.gov/pubmed/25849399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004715001674 |
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