Mutational analysis of varicella-zoster virus (VZV) immediate early protein (IE62) subdomains and their importance in viral replication

VZV IE62 is an essential, immediate-early, tegument protein and consists of five domains. We generated recombinant viruses carrying mutations in the first three IE62 domains and tested their influence on VZV replication kinetics. The mutations in domain I did not affect replication kinetics while do...

Full description

Saved in:
Bibliographic Details
Published in:Virology
Main Authors: Khalil, Mohamed I., Che, Xibing, Sung, Philip, Sommer, Marvin H., Hay, John, Arvin, Ann M.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826839/
https://ncbi.nlm.nih.gov/pubmed/26914506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.02.012
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items