GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial

AIMS/HYPOTHESIS: Liraglutide is a glucagon-like peptide-1 (GLP-1) analogue that has been demonstrated to successfully treat diabetes and promote weight loss. The mechanisms by which liraglutide confers weight loss remain to be fully clarified. Thus, we investigated whether GLP-1 receptors are expres...

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Veröffentlicht in:Diabetologia
Hauptverfasser: Farr, Olivia M., Sofopoulos, Michail, Tsoukas, Michael A., Dincer, Fadime, Thakkar, Bindiya, Sahin-Efe, Ayse, Filippaios, Andreas, Bowers, Jennifer, Srnka, Alexandra, Gavrieli, Anna, Ko, Byung-Joon, Liakou, Chrysoula, Kanyuch, Nickole, Tseleni-Balafouta, Sofia, Mantzoros, Christos S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826792/
https://ncbi.nlm.nih.gov/pubmed/26831302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-3874-y
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