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Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study

BACKGROUND: The Long Life Family Study (LLFS) is an international study to identify the genetic components of various healthy aging phenotypes. We hypothesized that pedigree-specific rare variants at longevity-associated genes could have a similar functional impact on healthy phenotypes. METHODS: We...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:BMC Geriatr
Päätekijät: Druley, Todd E., Wang, Lihua, Lin, Shiow J., Lee, Joseph H., Zhang, Qunyuan, Daw, E. Warwick, Abel, Haley J., Chasnoff, Sara E., Ramos, Enrique I., Levinson, Benjamin T., Thyagarajan, Bharat, Newman, Anne B., Christensen, Kaare, Mayeux, Richard, Province, Michael A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826550/
https://ncbi.nlm.nih.gov/pubmed/27060904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12877-016-0253-y
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