Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study

BACKGROUND: The Long Life Family Study (LLFS) is an international study to identify the genetic components of various healthy aging phenotypes. We hypothesized that pedigree-specific rare variants at longevity-associated genes could have a similar functional impact on healthy phenotypes. METHODS: We...

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Detalhes bibliográficos
Publicado no:BMC Geriatr
Main Authors: Druley, Todd E., Wang, Lihua, Lin, Shiow J., Lee, Joseph H., Zhang, Qunyuan, Daw, E. Warwick, Abel, Haley J., Chasnoff, Sara E., Ramos, Enrique I., Levinson, Benjamin T., Thyagarajan, Bharat, Newman, Anne B., Christensen, Kaare, Mayeux, Richard, Province, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826550/
https://ncbi.nlm.nih.gov/pubmed/27060904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12877-016-0253-y
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