The inhibition of microRNAs by HIV-1 Tat suppresses beta catenin activity in astrocytes

BACKGROUND: Long term infection with HIV-1, even in the context of therapy, leads to chronic health problems including an array of neurocognitive dysfunctions. The viral Tat protein has previously been implicated in neuropathogenesis through its effect on astrocytes. Tat has also been shown to inhib...

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Bibliografische gegevens
Gepubliceerd in:Retrovirology
Hoofdauteurs: Sardo, Luca, Vakil, Priyal R., Elbezanti, Weam, El-Sayed, Anas, Klase, Zachary
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826512/
https://ncbi.nlm.nih.gov/pubmed/27060080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0256-y
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