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The inhibition of microRNAs by HIV-1 Tat suppresses beta catenin activity in astrocytes

BACKGROUND: Long term infection with HIV-1, even in the context of therapy, leads to chronic health problems including an array of neurocognitive dysfunctions. The viral Tat protein has previously been implicated in neuropathogenesis through its effect on astrocytes. Tat has also been shown to inhib...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Sardo, Luca, Vakil, Priyal R., Elbezanti, Weam, El-Sayed, Anas, Klase, Zachary
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826512/
https://ncbi.nlm.nih.gov/pubmed/27060080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0256-y
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