The inhibition of microRNAs by HIV-1 Tat suppresses beta catenin activity in astrocytes

BACKGROUND: Long term infection with HIV-1, even in the context of therapy, leads to chronic health problems including an array of neurocognitive dysfunctions. The viral Tat protein has previously been implicated in neuropathogenesis through its effect on astrocytes. Tat has also been shown to inhib...

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Udgivet i:Retrovirology
Main Authors: Sardo, Luca, Vakil, Priyal R., Elbezanti, Weam, El-Sayed, Anas, Klase, Zachary
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826512/
https://ncbi.nlm.nih.gov/pubmed/27060080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0256-y
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