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The inhibition of microRNAs by HIV-1 Tat suppresses beta catenin activity in astrocytes

BACKGROUND: Long term infection with HIV-1, even in the context of therapy, leads to chronic health problems including an array of neurocognitive dysfunctions. The viral Tat protein has previously been implicated in neuropathogenesis through its effect on astrocytes. Tat has also been shown to inhib...

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Détails bibliographiques
Publié dans:Retrovirology
Auteurs principaux: Sardo, Luca, Vakil, Priyal R., Elbezanti, Weam, El-Sayed, Anas, Klase, Zachary
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826512/
https://ncbi.nlm.nih.gov/pubmed/27060080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0256-y
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