A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17(+) cell frequency

Patients with HPV-positive oropharyngeal squamous cell carcinomas (OPSCCs) have a better prognosis than patients with non-HPV-induced OPSCC. The role of the immune response in this phenomenon is yet unclear. We studied the number of T cells, regulatory T cells (Tregs), T helper 17 (Th17) cells and I...

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Bibliographic Details
Published in:Cancer Immunol Immunother
Main Authors: Punt, Simone, Dronkers, Emilie A. C., Welters, Marij J. P., Goedemans, Renske, Koljenović, Senada, Bloemena, Elisabeth, Snijders, Peter J. F., Gorter, Arko, van der Burg, Sjoerd H., de Jong, Robert J. Baatenburg, Jordanova, Ekaterina S.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826411/
https://ncbi.nlm.nih.gov/pubmed/26899388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1805-x
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