A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17(+) cell frequency

Patients with HPV-positive oropharyngeal squamous cell carcinomas (OPSCCs) have a better prognosis than patients with non-HPV-induced OPSCC. The role of the immune response in this phenomenon is yet unclear. We studied the number of T cells, regulatory T cells (Tregs), T helper 17 (Th17) cells and I...

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Publicat a:Cancer Immunol Immunother
Autors principals: Punt, Simone, Dronkers, Emilie A. C., Welters, Marij J. P., Goedemans, Renske, Koljenović, Senada, Bloemena, Elisabeth, Snijders, Peter J. F., Gorter, Arko, van der Burg, Sjoerd H., de Jong, Robert J. Baatenburg, Jordanova, Ekaterina S.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826411/
https://ncbi.nlm.nih.gov/pubmed/26899388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1805-x
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