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A chemical screen to identify inducers of the mitochondrial unfolded protein response in C. elegans

We previously showed that inhibition of the mevalonate pathway in C. elegans causes inhibition of protein prenylation, developmental arrest and lethality. We also showed that constitutive activation of the mitochondrial unfolded protein response, UPR(mt), is an effective way for C. elegans to become...

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Detalhes bibliográficos
Publicado no:Worm
Main Authors: Rauthan, Manish, Pilon, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826155/
https://ncbi.nlm.nih.gov/pubmed/27123370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21624054.2015.1096490
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