The C. elegans Ortholog of USP7 controls DAF-16 stability in Insulin/IGF-1-like signaling

FOXO family transcription factors are downstream effectors of Insulin/IGF-1 signaling (IIS) and are regulated by posttranslational modification and coregulators, including components of the ubiquitin-proteasome system (UPS). Cofactors promoting DAF-16/FOXO protein stability and function in IIS have...

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Publicat a:Worm
Autors principals: Heimbucher, Thomas, Hunter, Tony
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Commentary
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826154/
https://ncbi.nlm.nih.gov/pubmed/27123371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21624054.2015.1103429
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