Dianxianning improved amyloid β-induced pathological characteristics partially through DAF-2/DAF-16 insulin like pathway in transgenic C. elegans

Dianxianning (DXN) is a traditional Chinese formula, and has been approved in China for treating epilepsy since 1996. Here anti-Alzheimer’s disease activity of DXN has been reported. DXN improved AD-like symptoms of paralysis and 5-HT sensitivity of transgenic Aβ(1-42) C. elegans. In worms, DXN sign...

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Publicat a:Sci Rep
Autors principals: Zhi, Dejuan, Wang, Dong, Yang, Wenqi, Duan, Ziyun, Zhu, Shuqian, Dong, Juan, Wang, Na, Wang, Ningbo, Fei, Dongqing, Zhang, Zhanxin, Wang, Xin, Wang, Meizhu, Li, Hongyu
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595840/
https://ncbi.nlm.nih.gov/pubmed/28900141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11628-9
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