FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection

The immune mechanisms that recognize inhaled Aspergillus fumigatus conidia to promote their elimination from the lungs are incompletely understood. FleA is a lectin expressed by Aspergillus fumigatus that has twelve binding sites for fucosylated structures that are abundant in the glycan coats of mu...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kerr, Sheena C., Fischer, Gregory J., Sinha, Meenal, McCabe, Orla, Palmer, Jonathan M., Choera, Tsokyi, Yun Lim, Fang, Wimmerova, Michaela, Carrington, Stephen D., Yuan, Shaopeng, Lowell, Clifford A., Oscarson, Stefan, Keller, Nancy P., Fahy, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825926/
https://ncbi.nlm.nih.gov/pubmed/27058347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005555
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