Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature

Targeted RNA delivery to lung endothelial cells has the potential to treat conditions that involve inflammation, such as chronic asthma and obstructive pulmonary disease. To this end, chemically modified dendrimer nanomaterials were synthesized and optimized for targeted small interfering RNA (siRNA...

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發表在:Nano Lett
Main Authors: Khan, Omar F., Zaia, Edmond W., Jhunjhunwala, Siddharth, Xue, Wen, Cai, Wenxin, Yun, Dong Soo, Barnes, Carmen M., Dahlman, James E., Dong, Yizhou, Pelet, Jeisa M., Webber, Matthew J., Tsosie, Jonathan K., Jacks, Tyler E., Langer, Robert, Anderson, Daniel G.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825876/
https://ncbi.nlm.nih.gov/pubmed/25789998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl5048972
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