Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature

Targeted RNA delivery to lung endothelial cells has the potential to treat conditions that involve inflammation, such as chronic asthma and obstructive pulmonary disease. To this end, chemically modified dendrimer nanomaterials were synthesized and optimized for targeted small interfering RNA (siRNA...

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Detaylı Bibliyografya
Yayımlandı:Nano Lett
Asıl Yazarlar: Khan, Omar F., Zaia, Edmond W., Jhunjhunwala, Siddharth, Xue, Wen, Cai, Wenxin, Yun, Dong Soo, Barnes, Carmen M., Dahlman, James E., Dong, Yizhou, Pelet, Jeisa M., Webber, Matthew J., Tsosie, Jonathan K., Jacks, Tyler E., Langer, Robert, Anderson, Daniel G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825876/
https://ncbi.nlm.nih.gov/pubmed/25789998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl5048972
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