Non-integrating episomal plasmid-based reprogramming of human amniotic fluid stem cells into induced pluripotent stem cells in chemically defined conditions

Amniotic fluid stem cells (AFSC) represent an attractive potential cell source for fetal and pediatric cell-based therapies. However, upgrading them to pluripotency confers refractoriness toward senescence, higher proliferation rate and unlimited differentiation potential. AFSC were observed to rapi...

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Vydáno v:Cell Cycle
Hlavní autoři: Slamecka, Jaroslav, Salimova, Lilia, McClellan, Steven, van Kelle, Mathieu, Kehl, Debora, Laurini, Javier, Cinelli, Paolo, Owen, Laurie, Hoerstrup, Simon P, Weber, Benedikt
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825845/
https://ncbi.nlm.nih.gov/pubmed/26654216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121332
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