Non-integrating episomal plasmid-based reprogramming of human amniotic fluid stem cells into induced pluripotent stem cells in chemically defined conditions

Amniotic fluid stem cells (AFSC) represent an attractive potential cell source for fetal and pediatric cell-based therapies. However, upgrading them to pluripotency confers refractoriness toward senescence, higher proliferation rate and unlimited differentiation potential. AFSC were observed to rapi...

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Gepubliceerd in:Cell Cycle
Hoofdauteurs: Slamecka, Jaroslav, Salimova, Lilia, McClellan, Steven, van Kelle, Mathieu, Kehl, Debora, Laurini, Javier, Cinelli, Paolo, Owen, Laurie, Hoerstrup, Simon P, Weber, Benedikt
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
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Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825845/
https://ncbi.nlm.nih.gov/pubmed/26654216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121332
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