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Non-integrating episomal plasmid-based reprogramming of human amniotic fluid stem cells into induced pluripotent stem cells in chemically defined conditions

Amniotic fluid stem cells (AFSC) represent an attractive potential cell source for fetal and pediatric cell-based therapies. However, upgrading them to pluripotency confers refractoriness toward senescence, higher proliferation rate and unlimited differentiation potential. AFSC were observed to rapi...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Slamecka, Jaroslav, Salimova, Lilia, McClellan, Steven, van Kelle, Mathieu, Kehl, Debora, Laurini, Javier, Cinelli, Paolo, Owen, Laurie, Hoerstrup, Simon P, Weber, Benedikt
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825845/
https://ncbi.nlm.nih.gov/pubmed/26654216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121332
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