Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under ATM or p53 inhibition

Previously we demonstrated that endometrium-derived human mesenchymal stem cells (hMESCs) via activation of the ATM/p53/p21/Rb pathway enter the premature senescence in response to oxidative stress. Down regulation effects of the key components of this signaling pathway, particularly ATM and p53, on...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Borodkina, Aleksandra V., Shatrova, Alla N., Deryabin, Pavel I., Grukova, Anastasiya A., Nikolsky, Nikolay N., Burova, Elena B.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825783/
https://ncbi.nlm.nih.gov/pubmed/26636375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121326
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