Loading...
MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans
The Caenorhabditis elegans DEG/ENaC proteins MEC-4 and MEC-10 transduce gentle touch in the six touch receptor neurons . Gain-of-function mutations of mec-4 and mec-4(d) result in a hyperactive channel and neurodegeneration in vivo. Loss of MEC-6, a putative DEG/ENaC-specific chaperone, and of the s...
Saved in:
| Published in: | G3 (Bethesda) |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Genetics Society of America
2016
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825646/ https://ncbi.nlm.nih.gov/pubmed/27172609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.023507 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|