Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines

Anti-integrin-linked kinase (ILK) therapies result in aberrant mitosis including altered mitotic spindle organization, centrosome declustering and mitotic arrest. In contrast to cells that expressed the retinoblastoma tumor suppressor protein Rb, we have shown that in retinoblastoma cell lines that...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Duminuco, Rose, Noble, Jake W, Goody, Joseph, Sharma, Manju, Ksander, Bruce R, Roskelley, Calvin D, Cox, Michael E, Mills, Julia
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825635/
https://ncbi.nlm.nih.gov/pubmed/26176204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1064205
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