Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines

Anti-integrin-linked kinase (ILK) therapies result in aberrant mitosis including altered mitotic spindle organization, centrosome declustering and mitotic arrest. In contrast to cells that expressed the retinoblastoma tumor suppressor protein Rb, we have shown that in retinoblastoma cell lines that...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Duminuco, Rose, Noble, Jake W, Goody, Joseph, Sharma, Manju, Ksander, Bruce R, Roskelley, Calvin D, Cox, Michael E, Mills, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825635/
https://ncbi.nlm.nih.gov/pubmed/26176204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1064205
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