Salarin C inhibits the maintenance of chronic myeloid leukemia progenitor cells

We previously showed that incubation of chronic myeloid leukemia (CML) cells in very low oxygen selects a cell subset where the oncogenetic BCR/Abl protein is suppressed and which is thereby refractory to tyrosine kinase inhibitors used for CML therapy. In this study, salarin C, an anticancer macrol...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Del Poggetto, E, Tanturli, M, Ben-Califa, N, Gozzini, A, Tusa, I, Cheloni, G, Marzi, I, Cipolleschi, MG, Kashman, Y, Neumann, D, Rovida, E, Dello Sbarba, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825620/
https://ncbi.nlm.nih.gov/pubmed/26291130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1078029
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