Shifts in rDNA levels act as a genome buffer promoting chromosome homeostasis

The nucleolus is considered to be a stress sensor and rDNA-based regulation of cellular senescence and longevity has been proposed. However, the role of rDNA in the maintenance of genome integrity has not been investigated in detail. Using genomically diverse industrial yeasts as a model and array-b...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Deregowska, Anna, Adamczyk, Jagoda, Kwiatkowska, Aleksandra, Gurgul, Artur, Skoneczny, Marek, Skoneczna, Adrianna, Szmatola, Tomasz, Jasielczuk, Igor, Magda, Michal, Rawska, Ewa, Pabian, Sylwia, Panek, Anita, Kaplan, Jakub, Lewinska, Anna, Wnuk, Maciej
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
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Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825570/
https://ncbi.nlm.nih.gov/pubmed/26566866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1093705
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