Shifts in rDNA levels act as a genome buffer promoting chromosome homeostasis

The nucleolus is considered to be a stress sensor and rDNA-based regulation of cellular senescence and longevity has been proposed. However, the role of rDNA in the maintenance of genome integrity has not been investigated in detail. Using genomically diverse industrial yeasts as a model and array-b...

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Dettagli Bibliografici
Pubblicato in:Cell Cycle
Autori principali: Deregowska, Anna, Adamczyk, Jagoda, Kwiatkowska, Aleksandra, Gurgul, Artur, Skoneczny, Marek, Skoneczna, Adrianna, Szmatola, Tomasz, Jasielczuk, Igor, Magda, Michal, Rawska, Ewa, Pabian, Sylwia, Panek, Anita, Kaplan, Jakub, Lewinska, Anna, Wnuk, Maciej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
Soggetti:
Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825570/
https://ncbi.nlm.nih.gov/pubmed/26566866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1093705
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