Shifts in rDNA levels act as a genome buffer promoting chromosome homeostasis

The nucleolus is considered to be a stress sensor and rDNA-based regulation of cellular senescence and longevity has been proposed. However, the role of rDNA in the maintenance of genome integrity has not been investigated in detail. Using genomically diverse industrial yeasts as a model and array-b...

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Publicado en:Cell Cycle
Autores principales: Deregowska, Anna, Adamczyk, Jagoda, Kwiatkowska, Aleksandra, Gurgul, Artur, Skoneczny, Marek, Skoneczna, Adrianna, Szmatola, Tomasz, Jasielczuk, Igor, Magda, Michal, Rawska, Ewa, Pabian, Sylwia, Panek, Anita, Kaplan, Jakub, Lewinska, Anna, Wnuk, Maciej
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825570/
https://ncbi.nlm.nih.gov/pubmed/26566866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1093705
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