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Shifts in rDNA levels act as a genome buffer promoting chromosome homeostasis
The nucleolus is considered to be a stress sensor and rDNA-based regulation of cellular senescence and longevity has been proposed. However, the role of rDNA in the maintenance of genome integrity has not been investigated in detail. Using genomically diverse industrial yeasts as a model and array-b...
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| Опубликовано в: : | Cell Cycle |
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| Главные авторы: | , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825570/ https://ncbi.nlm.nih.gov/pubmed/26566866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1093705 |
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