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α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology
BACKGROUND: Passive and active immunization with α-synuclein has been shown to be neuroprotective in animal models of Parkinson’s disease. We have previously shown that vaccination with α-synuclein, long before α-synuclein-induced brain pathology, prevents striatal degeneration by inducing regulator...
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| Pubblicato in: | J Neuroinflammation |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825077/ https://ncbi.nlm.nih.gov/pubmed/27055651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0532-8 |
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