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α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology

BACKGROUND: Passive and active immunization with α-synuclein has been shown to be neuroprotective in animal models of Parkinson’s disease. We have previously shown that vaccination with α-synuclein, long before α-synuclein-induced brain pathology, prevents striatal degeneration by inducing regulator...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Christiansen, Josefine R., Olesen, Mads N., Otzen, Daniel E., Romero-Ramos, Marina, Sanchez-Guajardo, Vanesa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825077/
https://ncbi.nlm.nih.gov/pubmed/27055651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0532-8
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