CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology

We have previously shown that immunological processes in the brain during α-synuclein-induced neurodegeneration vary depending on the presence or absence of cell death. This suggests that the immune system is able to react differently to the different stages of α-synuclein pathology. However, it was...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Olesen, Mads N., Christiansen, Josefine R., Petersen, Steen Vang, Jensen, Poul Henning, Paslawski, Wojciech, Romero-Ramos, Marina, Sanchez-Guajardo, Vanesa
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857520/
https://ncbi.nlm.nih.gov/pubmed/29560431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2018.e00513
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