Hydroxyurea Therapy for Children With Sickle Cell Anemia in Sub‐Saharan Africa: Rationale and Design of the REACH Trial

BACKGROUND: Sickle cell anemia (SCA) is an inherited hematological disorder that causes a large but neglected global health burden, particularly in Africa. Hydroxyurea represents the only available disease‐modifying therapy for SCA, and has proven safety and efficacy in high‐resource countries. In s...

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Vydáno v:Pediatr Blood Cancer
Hlavní autoři: McGann, Patrick T., Tshilolo, Léon, Santos, Brigida, Tomlinson, George A., Stuber, Susan, Latham, Teresa, Aygun, Banu, Obaro, Stephen K., Olupot‐Olupot, Peter, Williams, Thomas N., Odame, Isaac, Ware, Russell E.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825070/
https://ncbi.nlm.nih.gov/pubmed/26275071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25705
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