An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease

There is a clinical need for new, more effective treatments for chronic and debilitating inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. Targeting drugs selectively to the inflamed intestine may improve therapeutic outcomes and minimize systemic toxicity. We repor...

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Pubblicato in:Sci Transl Med
Autori principali: Zhang, Sufeng, Ermann, Joerg, Succi, Marc D., Zhou, Allen, Hamilton, Matthew J., Cao, Bonnie, Korzenik, Joshua R., Glickman, Jonathan N., Vemula, Praveen K., Glimcher, Laurie H., Traverso, Giovanni, Langer, Robert, Karp, Jeffrey M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825054/
https://ncbi.nlm.nih.gov/pubmed/26268315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa5657
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